Glyceryl Glycyrrhetinate
AKA “RefChem:663529, NNYMAFQJECSMTN-YZADGDQXSA-N”
Synthetic
Ingredient Facts
Glyceryl glycyrrhetinate
AKA: RefChem:663529, NNYMAFQJECSMTN-YZADGDQXSA-N
Synthetic · Soothing · EWG: 4
Synthetic
Cleanser
Soothing
Emulsifier
Skin Conditioner
Synthetic
Clean
Helps blend oil and water-based ingredients into a smooth, unified formula so products apply evenly and feel luxurious on skin.
Formula
C33H52O6
Mol. Weight
544.80
CAS #
108916-85-4
Form
Powder
See origin →
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emulsifier
Mixes Oil & Water
Traditional Use
Synthetic ester derived from glycerin and glycyrrhetinic acid (licorice root extract). Developed to stabilize and deliver the anti-inflammatory benefits of licorice in skincare products.
Skin Types
●all-skin-types
Best For
Irritation
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Final Report on the Safety Assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammon
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Glyceryl Glycyrrhetinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR