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Hexanediol Distearate
AKA “1, 6-Hexanediol distearate, 1LF5H7G01B, Octadecanoic acid, 6-hexanediyl ester, 6-Hexanediol stearic acid diester, EINECS 247-947-8, 6-HEXANEDIOL, DISTEARATE, 1'-(1, 6-hexanediyl) ester, 6-Hexanediol, octadecanoic acid ester, STEARIC ACID, HEXAMETHYLENE ESTER”
Skin Conditioning
Ingredient Facts
Hexanediol distearate
AKA: 1, 6-Hexanediol distearate, 1LF5H7G01B, Octadecanoic acid, 6-hexanediyl ester, 6-Hexanediol stearic acid diester, EINECS 247-947-8, 6-HEXANEDIOL, 1'-(1, 6-hexanediyl) ester, 6-Hexanediol, Octadecanoic acid ester, STEARIC ACID, HEXAMETHYLENE ESTER
Skin Conditioning · Skin Conditioning · EWG: 4
Plant-Derived
Skin Conditioner
Not Clean
Hexamethylene distearate
Formula
C42H82O4
Mol. Weight
651.10
CAS #
26730-92-7
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Viscosity Controlling
Locks in moisture
Traditional Use
A synthetic ester developed in the 20th century as a conditioning agent and emollient in cosmetics. Designed to improve skin feel and spreadability in creams and lotions.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Amended Final Report on the Safety Assessment of Hydroxystearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report of the Safety Assessment of Lithium Stearate, Aluminum Distearate, Aluminum Stearate, Aluminum Tristearate, Ammonium Stearate, Calcium Stearate, Magnesium Stearate, Potassium Stearate, So
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Glycol Stearate, Glycol Stearate SE, and Glycol Distearate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Isostearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of PEG-2, -3, -4, -6, -8, -9, -12, -20, -32, -50, -75, -120, -150, and -175 Distearate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Sorbitan Caprylate, Sorbitan Cocoate, Sorbitan Diisostearate, Sorbitan Dioleate, Sorbitan Distearate, Sorbitan Isostearate, Sorbitan Olivate, Sorbitan Sesquiis
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report: Safety Assessment of Polyhydroxystearic Acid, Poly(3-Hydroxyoctanoic Acid, and Polylactic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Re-evaluation: Safety Assessment of Hydroxystearic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
10-Hydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Aluminum Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glyceryl Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycol Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hexanediol Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-12 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-12 Glyceryl Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-120 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-150 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-175 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-190 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-2 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Methyl Glucose Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-23 Glyceryl Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-250 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-3 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-32 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-4 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-4 Glyceryl Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-4 Polyglyceryl-2 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-6 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-75 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-8 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-9 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Polyglyceryl-10 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Polyglyceryl-2 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Polyglyceryl-3 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Polyglyceryl-4 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Polyglyceryl-6 Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Polyhydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-20 Methyl Glucose Ether Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Stearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Aluminum Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glyceryl Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycol Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Isostearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-12 Glyceryl Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-150 Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Methyl Glucose Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-23 Glyceryl Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-3 Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-8 Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Polyglyceryl-10 Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Polyglyceryl-3 Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Polyhydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PPG-20 Methyl Glucose Ether Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Stearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Simultaneous contact sensitivity to hydroxystearic acid and C18-36 acid triglyceride in lip glosses.
Kimura M, Kawada A, Ogino M, Murayama Y
Contact dermatitis, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
PEG-23 glyceryl distearate, a multifunctional skin-supporting material, upregulates the expression of factors associated with epidermal barrier and hy
Miyoshi T, Keller BC, Nakagawa S, Ashino T, Numazawa S
International journal of cosmetic science, 2025
→
Microemulsions based on TPGS and isostearic acid for imiquimod formulation and skin delivery.
Pescina S, Garrastazu G, Del Favero E, Rondelli V, Cantù L et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018
→
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
→
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
→
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
→
The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension.
Slevin ML, Piall EM, Johnston A, Levison DA, Aherne GW et al.
Investigational new drugs, 1984
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR