Human Placental Protein
AKA “placental protein, hydrolyzed placenta
Synthetic
Ingredient Facts
Human placental protein
AKA: Hydrolyzed placenta
Synthetic · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Synthetic
Clean
Science: Functions: Hair Conditioning, Skin Conditioning Safety Ratings: CIR: Safe as used EU Restriction: II/416
CAS #
-
Form
Powder
State
Solid
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Placental proteins entered cosmetic use in the early-to-mid 20th century, especially in Japanese skincare, based on theories that placental biomolecules could stimulate skin regeneration and collagen synthesis. Use remains ethically contested and is now largely replaced by plant and biotech alternatives.
Skin Types
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUpermitted
JAPANpermitted
CANADApermitted
Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydro
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Hydrolyzed Placental Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
Placental Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydrolyzed Placental Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Placental Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Verified Feb 2026
Data: CosIng · EWG · CIR