Hydrolyzed Fibronectin
AKA “Fibronectin Hydrolysate, Soluble Fibronectin
Synthetic
Ingredient Facts
Hydrolyzed fibronectin
AKA: Fibronectin Hydrolysate, Soluble Fibronectin
Synthetic · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Synthetic
Clean
A protein derived from fibronectin that strengthens and softens both hair and skin, helping to lock in moisture and improve texture.
Effective at 8.25%
CAS #
100085-35-6
Form
Powder
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Fibronectin is a human protein identified in the 1970s; the hydrolyzed form was later developed for cosmetics as a modern ingredient to support skin matrix and conditioning properties.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
4e-06%
16.5%
0%100%
Effective Range
CIR reported use: 0.000004-6 | 0.00003-16.5
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: CosIng · EWG · CIR