Hydroxyacetophenone
AKA “4'-Hydroxyacetophenone, 1-(4-Hydroxyphenyl)ethanone, 4-Hydroxyacetophenone, P-HYDROXYACETOPHENONE, 4-Acetylphenol, p-Hydroxyphenyl methyl ketone, Ethanone, Methyl p-hydroxyphenyl ketone
Synthetic
Ingredient Facts
Hydroxyacetophenone
AKA: 4'-Hydroxyacetophenone, 1-(4-Hydroxyphenyl)ethanone, 4-Hydroxyacetophenone, P-HYDROXYACETOPHENONE, 4-Acetylphenol, P-Hydroxyphenyl methyl ketone, Ethanone, Methyl p-hydroxyphenyl ketone
Synthetic · Antioxidant · EWG: 4
Synthetic
Antioxidant
Preservative
Anti-Aging
Safety Concern
Synthetic
Clean
A naturally-derived antioxidant that helps protect skin from environmental damage and supports a youthful complexion.
Solubility Practically insoluble or insoluble in water
Formula
C8H8O2
Mol. Weight
136.15
CAS #
99-93-4
Form
Powder
State
Dry Powder; Other Solid
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Anti-Aging
Targets fine lines, wrinkles, or loss of firmness. Works by boosting collagen, speeding cell turnover, or both.
Neutralizes Free Radicals
Traditional Use
Developed as a modern synthetic preservative and antioxidant in the late 20th century for use in cosmetic formulations, created to replace some natural preservatives with improved stability.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
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Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR