Isopropyl Thioglycolate
AKA “EINECS 230-956-6, Acetic acid, isopropyl ester, 1-methylethyl ester, THIOGLYCOLIC ACID ISOPROPYL ESTER, ACETIC ACID, 1-METHYLETHYL ESTER”
Synthetic
Ingredient Facts
Isopropyl thioglycolate
AKA: EINECS 230-956-6, Acetic acid, Isopropyl ester, 1-methylethyl ester, THIOGLYCOLIC ACID ISOPROPYL ESTER, ACETIC ACID, 1-METHYLETHYL ESTER
Synthetic · Hair Waving Or Straightening · EWG: 4
Synthetic
Synthetic
Clean
A conditioning agent that helps relax and reshape hair texture, creating smooth waves or straight styles that last longer.
Formula
C5H10O2S
Mol. Weight
134.20
CAS #
7383-61-1
Form
Liquid
See origin →
Functions
Hair Waving Or Straightening
Reducing Agent
Anti-Inflammatory
Antioxidant
Protects skin from free radical damage caused by UV, pollution, and stress
Improves Elasticity
Changes hair texture
Traditional Use
Developed in the mid-20th century as a chemical depilatory and hair-waving agent. Created to replace older, more caustic hair removal methods by offering safer controlled protein breakdown.
Skin Types
●all-skin-types
Best For
Rough Texture
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Final Report on the Safety Assessment of Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Acetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
dehydroacetic acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isopropyl Ester of PVM/MA Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isopropyl Thioglycolate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
dehydroacetic acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isopropyl Ester of PVM/MA Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Potential application of novel liquid crystal nanoparticles of isostearyl glyceryl ether for transdermal delivery of 4-biphenyl acetic acid.
Fujii MY, Asakawa Y, Fukami T
International journal of pharmaceutics, 2020
Preparation of (13)C-labeled ceramide by acetic acid bacteria and its incorporation in mice.
Fukami H, Tachimoto H, Kishi M, Kaga T, Waki H et al.
Journal of lipid research, 2010
Trichloroacetic acid
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR