Isostearamidopropyl Morpholine Lactate
AKA “INCROMATE ISML, RICHAMATE ISML, MACKALENE 426, DIMETHYLAMINOPROPYLALKONIUM MORPHOLINE LACTATE, RefChem:792342, ISOSTEARAMIDOPROPYL MORPHOLINE (+-)-LACTATE, ISOSTEARAMIDOPROPYL MORPHOLINE LACTATE [INCI]
Synthetic
Ingredient Facts
Isostearamidopropyl morpholine lactate
AKA: INCROMATE ISML, RICHAMATE ISML, MACKALENE 426, DIMETHYLAMINOPROPYLALKONIUM MORPHOLINE LACTATE, RefChem:792342, ISOSTEARAMIDOPROPYL MORPHOLINE (+-)-LACTATE, ISOSTEARAMIDOPROPYL MORPHOLINE LACTATE [INCI]
Synthetic · Antistatic · EWG: 4
Plant-Derived
Skin Conditioner
Hair Care
Synthetic
Clean
Helps reduce frizz and static in hair while keeping strands smooth and manageable throughout the day.
Formula
C28H56N2O5
Mol. Weight
500.80
CAS #
72300-24-4, 133651-38-4
Form
Liquid
See origin →
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Reduces Static
Reduces Flyaways
Traditional Use
Developed as a modern conditioning agent in the cosmetics industry. Created to provide hair and skin conditioning properties with improved stability and mildness compared to earlier synthetic alternatives.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR