Isostearyl Sebacate
AKA “UNII-S78O3FPG9R, Isostearyl sebacate [INCI], RefChem:149999
Synthetic
Ingredient Facts
Isostearyl sebacate
AKA: UNII-S78O3FPG9R, Isostearyl sebacate [INCI], RefChem:149999
Synthetic · Emollient · EWG: 4
Plant-Derived
Emollient
Occlusive
Skin Conditioner
Synthetic
Clean
A lightweight emollient derived from natural sources that softens and conditions skin, helping it feel smooth and hydrated.
Formula
C28H54O4
Mol. Weight
454.70
CAS #
478273-24-4
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Skin Conditioning Miscellaneous
Antioxidant Protection
Locks In Moisture
UV Protection
Improves skin feel
Traditional Use
A synthetic ester created as a cosmetic emollient and skin conditioning agent. Developed to provide hydration and improved texture in skincare formulations.
Skin Types
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR