Magnesium Acetate
AKA “Magnesium diacetate, ACETIC ACID, MAGNESIUM SALT, Mg Acetate, Magnesium di(acetate), Acetic acid magnesium salt, Mg(II) acetate, Magnesium acetate anhydrous
Synthetic
Ingredient Facts
Magnesium acetate
AKA: Magnesium diacetate, ACETIC ACID, MAGNESIUM SALT, Mg Acetate, Magnesium di(acetate), Acetic acid magnesium salt, Mg(II) acetate, Magnesium acetate anhydrous
Synthetic · Buffering · EWG: 4
Synthetic
Skin Conditioner
Synthetic
Clean
A mineral that helps stabilize the formula's pH, keeping the product balanced and effective on skin.
Formula
C4H6MgO4
Mol. Weight
142.39
CAS #
142-72-3
Form
Powder
State
Liquid; Pellets or Large Crystals
See origin →
Functions
Buffering
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Anti-Inflammatory
Fights Acne
Antioxidant
Protects skin from free radical damage caused by UV, pollution, and stress
Maintains optimal pH
Traditional Use
A salt form of magnesium developed for cosmetic and pharmaceutical use in the 20th century; used primarily as a preservative and antimicrobial agent in skincare formulations.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Mild Irritant
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Final Report on the Safety Assessment of Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Acetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
dehydroacetic acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Magnesium Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Evaluation of calcium magnesium acetate and road salt for contact hypersensitivity potential and dermal irritancy in humans.
Cushman JR, Duff VA, Buteau GH, Aust LB, Caldwell N et al.
Contact dermatitis, 1991
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
dehydroacetic acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Magnesium Acetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Potential application of novel liquid crystal nanoparticles of isostearyl glyceryl ether for transdermal delivery of 4-biphenyl acetic acid.
Fujii MY, Asakawa Y, Fukami T
International journal of pharmaceutics, 2020
Preparation of (13)C-labeled ceramide by acetic acid bacteria and its incorporation in mice.
Fukami H, Tachimoto H, Kishi M, Kaga T, Waki H et al.
Journal of lipid research, 2010
Trichloroacetic acid
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR