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Magnesium Thioglycolate
AKA “UNII-8E96N0WA3X, EINECS 264-358-1, MAGNESIUM, BIS(MERCAPTOACETATO-O, RefChem:155278”
Synthetic
Ingredient Facts
Magnesium thioglycolate
AKA: UNII-8E96N0WA3X, EINECS 264-358-1, BIS(MERCAPTOACETATO-O, RefChem:155278
Synthetic · Depilatory · EWG: 4
Synthetic
Synthetic
Clean
A chemical compound that helps break down hair structure for hair removal, waving, or straightening treatments. Commonly used in depilatory products.
Formula
C4H6MgO4S2
Mol. Weight
206.50
CAS #
63592-16-5
Form
Powder
See origin →
Functions
Depilatory
Hair Waving Or Straightening
Reducing
Anti-Inflammatory
Fights Acne
Antioxidant
Protects skin from free radical damage caused by UV, pollution, and stress
Changes hair texture
Removes unwanted hair
Chemical reduction
Traditional Use
A modern chemical compound developed in the 20th century. Created as the active ingredient in alkaline hair permanent waves and hair removal products to break down hair's disulfide bonds.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
1%
0%1%
Reg. Limit
EU regulatory limit: 1%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 24.
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Mesoporous magnesium carbonate for use in powder cosmetics.
Bamford E, Grahn A, Århammar C, Ajaxon I, Annerén C
International journal of cosmetic science, 2021
→
Final Report of the Safety Assessment of Lithium Stearate, Aluminum Distearate, Aluminum Stearate, Aluminum Tristearate, Ammonium Stearate, Calcium Stearate, Magnesium Stearate, Potassium Stearate, So
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Aluminum Silicate, Calcium Silicate, Magnesium Aluminum Silicate, Magnesium Silicate, Magnesium Trisilicate, Sodium Magnesium Silicate, Zirconium Silicate, Att
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Silica, Alumina Magnesium Metasilicate, Aluminum Calcium Sodium Silicate, Aluminum Iron Silicates, Hydrated Silica and Potassium Aluminum Silicate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Magnesium Sulfate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Alumina Magnesium Metasilicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Aluminum Iron Calcium Magnesium Germanium Silicates
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Aluminum Iron Calcium Magnesium Zirconium Silicates
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Calcium Magnesium Silicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ethylene/Magnesium Acrylate Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Lithium Magnesium Silicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Lithium Magnesium Sodium Silicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Alginate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Aluminometasilicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Aluminum Silicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Ascorbate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Ascorbyl Phosphate [Vitamin C]
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Aspartate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Benzoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Carbonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Citrate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Coceth Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Coco-Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Cocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Glycinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Hydrogen Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Hydroxide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Isododecylbenzenesulfonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Lanolate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Laureth Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Laureth-3 Sulfosuccinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Methyl Cocoyl Taurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Myreth Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Myristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Oleth Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Palmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Palmitoyl Glutamate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium PCA
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Silicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Tallowate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Thioglycolate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Trisilicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium/TEA-Coco-Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Magnesium Silicate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Trimagnesium Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Evaluation of calcium magnesium acetate and road salt for contact hypersensitivity potential and dermal irritancy in humans.
Cushman JR, Duff VA, Buteau GH, Aust LB, Caldwell N et al.
Contact dermatitis, 1991
→
Microstructural, Fluid Dynamic, and Mechanical Characterization of Zinc Oxide and Magnesium Chloride-Modified Hydrogel Scaffolds.
de Mello Innocentini MD, Fuzatto Bueno BR, Urbaś A, Morawska-Chochół A
ACS biomaterials science & engineering, 2024
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and
Elmore AR
International journal of toxicology, 2005
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate,
Elmore AR, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Alumina Magnesium Metasilicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Lithium Magnesium Silicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Lithium Magnesium Sodium Silicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Acetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Aluminum Silicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Ascorbate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Ascorbyl Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Aspartate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Carbonate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Chloride
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Citrate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Cocoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Hydroxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Laurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Laureth Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Myristate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Oleth Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Oxide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Palmitate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Palmitoyl Glutamate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium PCA
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Silicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Trisilicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Magnesium Silicate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
A Case of Hailey-Hailey Disease Managed With Oral Magnesium Citrate and High-Dose Vitamin D(3).
Gu K, Silver S
Journal of cutaneous medicine and surgery, 2018
→
Magnesium peroxide
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
The preparation of lactoferrin/magnesium silicate lithium injectable hydrogel and application in promoting wound healing.
Wang B, Zhao J, Lu W, Ma Y, Wang X et al.
International journal of biological macromolecules, 2022
→
The preparation of lactoferrin/magnesium silicate lithium injectable hydrogel and application in promoting wound healing.
Wang B, Zhao J, Lu W, Ma Y, Wang X et al.
International journal of biological macromolecules, 2022
→
Sustained release of magnesium and zinc ions synergistica...
Fan Yang, Yijia Xue, Feilong Wang, Danni Guo, Yunjiao He, Xiao Zhao + 4 more
Bioactive materials, 2023
→
Development of magnesium hydroxide-doped nanofibrous spheres for repairing infected skin wounds.
You Y, Ning X, Zhang X, Wang Y, Zhang Y et al.
Biomaterials advances, 2024
→
Green electrospun Janus membrane of polyether block amide (PEBA) doped with hierarchical magnesium hydrogen phosphate for the removal of pharmaceutica
Zhu J, Wang X, Jiang Q, Duan J, Wang H
Journal of colloid and interface science, 2024
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR