Placental Protein
AKA “Placental Protein, Placenta-Derived Protein
Synthetic
Ingredient Facts
Placental protein
AKA: Placenta-Derived Protein
Synthetic · Humectant · EWG: 3
Synthetic
Humectant
Skin Conditioner
Synthetic
Clean
A natural protein that helps skin retain moisture, keeping it hydrated and supple throughout the day.
CAS #
84195-59-5
Form
Powder
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
Placental protein became a cosmetic ingredient in the early 20th century, particularly in anti-aging creams marketed in Europe and Japan. This is a modern development with no traditional medical or cosmetic history.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
3
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydro
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Hydrolyzed Placental Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
Placental Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydrolyzed Placental Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Placental Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Verified Feb 2026
Data: CosIng · EWG · CIR