Polyglyceryl-2 Diisostearate
AKA “Diglyceryl diisostearate, DERMOL DGDIS, MATSUNATE DI, RISOREX PGIS22, CITHROL PG 22IS, EINECS 267-821-6, SALACOS 42V, COSMOL 42V
Synthetic
Ingredient Facts
Polyglyceryl-2 diisostearate
AKA: Diglyceryl diisostearate, DERMOL DGDIS, MATSUNATE DI, RISOREX PGIS22, CITHROL PG 22IS, EINECS 267-821-6, SALACOS 42V, COSMOL 42V
Synthetic · Emollient · EWG: 4
Plant-Derived Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Synthetic
Clean
A natural emulsifier that helps blend water and oil-based ingredients together, creating a smooth, lightweight texture that absorbs easily into skin.
Formula
C42H82O7
Mol. Weight
699.10
CAS #
67938-21-0
See origin →
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emulsifier
Antioxidant Protection
UV Protection
Mixes Oil & Water
Traditional Use
Developed in the mid-20th century as a synthetic polyglyceryl ester emulsifier. Used in cosmetics to stabilize formulations and improve product texture.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR
Polyglyceryl-2 Diisostearate — Duck Heart Ghost