Polyglyceryl-2 Sesquiisostearate
AKA “Diglyceryl diisostearate, DERMOL DGDIS, MATSUNATE DI, RISOREX PGIS22, CITHROL PG 22IS, EINECS 267-821-6, SALACOS 42V, COSMOL 42V”
Synthetic
Ingredient Facts
Polyglyceryl-2 sesquiisostearate
AKA: Diglyceryl diisostearate, DERMOL DGDIS, MATSUNATE DI, RISOREX PGIS22, CITHROL PG 22IS, EINECS 267-821-6, SALACOS 42V, COSMOL 42V
Synthetic · Emollient · EWG: 4
Plant-Derived Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Plant Oil
Synthetic
Clean
A plant-derived ingredient that helps blend water and oil together, creating a smooth, unified texture in your cleanser or moisturizer.
Formula
C42H82O7
Mol. Weight
699.10
CAS #
67938-21-0
See origin →
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emulsifier
Antioxidant Protection
UV Protection
Mixes Oil & Water
Traditional Use
Developed as a modern emulsifier combining polyglycerin with isostearic acid. Created to improve texture and stability in contemporary skincare and makeup formulations.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR