Polyglyceryl-2 Tetraisostearate
AKA “Cithrol PG24IS, Salacos 44V, Cosmol 44V, S-FACE IS-204 P, UNII-KN8R167SEQ, RefChem:175154, PVQZOFSIXYDDHY-UHFFFAOYSA-N
Synthetic
Ingredient Facts
Polyglyceryl-2 tetraisostearate
AKA: Cithrol PG24IS, Salacos 44V, Cosmol 44V, S-FACE IS-204 P, UNII-KN8R167SEQ, RefChem:175154, PVQZOFSIXYDDHY-UHFFFAOYSA-N
Synthetic · Emollient · EWG: 4
Plant-Derived Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Synthetic
Clean
A naturally-derived emollient that helps stabilize formulas and condition skin, leaving it soft and smooth while gently cleansing without stripping moisture.
Formula
C78H150O9
Mol. Weight
1232.00
CAS #
121440-30-0
See origin →
Functions
Emulsion Stabilising
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Locks In Moisture
Traditional Use
Synthesized in the late 20th century as a stable emulsifier combining polyglycerin with isostearic acid. Created to improve formula stability and skin conditioning in modern skincare products.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR