Polyglyceryl-3 Triisostearate
AKA “Isostearic Acid Polyglyceryl Ester, Emollient
Synthetic
Ingredient Facts
Polyglyceryl-3 triisostearate
AKA: Isostearic Acid Polyglyceryl Ester, Emollient
Synthetic · Emollient · EWG: 4
Plant-Derived Synthetic
Emollient
Cleanser
Emulsifier
Skin Conditioner
Plant Oil
Synthetic
Clean
A natural emollient derived from plants that softens and conditions skin while helping other ingredients blend smoothly into formulas.
CAS #
66082-43-7
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
Traditional Use
A modern polyglyceryl emulsifier developed as a cosmetic ingredient with enhanced oil-binding capacity. Designed to create stable emulsions in skincare and color cosmetics with improved sensory feel.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Adverse Events from Emollient Use in Eczema: A Restricted Review of Published Data.
Bhanot A, Huntley A, Ridd MJ
Dermatology and therapy, 2019
Measurement of the biomechanical function and structure of ex vivo drying skin using raman spectral analysis and its modulation with emollient mixture
Biniek K, Tfayli A, Vyumvuhore R, Quatela A, Galliano MF et al.
Experimental dermatology, 2018
Measurement of the biomechanical function and structure of ex vivo drying skin using raman spectral analysis and its modulation with emollient mixture
Biniek K, Tfayli A, Vyumvuhore R, Quatela A, Galliano MF et al.
Experimental dermatology, 2018
Polyglyceryl-3 Triisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Emollients are more than sensory ingredients: the case of isostearyl isostearate.
Dederen JC, Chavan B, Rawlings AV
International journal of cosmetic science, 2012
Restoring Skin Hydration and Barrier Function: Mechanistic Insights Into Basic Emollients for Xerosis Cutis.
Fluhr JW, Muguet V, Christen-Zaech S
International journal of dermatology, 2025
Efficacy of an emollient containing diethylene glycol/dilinoleic acid copolymer for the treatment of dry skin and pruritus in patients with senile xer
Izumi R, Negi O, Suzuki T, Tominaga M, Kamo A et al.
Journal of cosmetic dermatology, 2017
Contact dermatitis caused by polyacrylamide/C13-4 isoparaffin/laureth-7 mix in an emollient cream for atopic skin.
Jaulent C, Dereure O, Raison-Peyron N
Contact dermatitis, 2019
Effect of emollients on UV filter absorbance and sunscreen efficiency.
Sohn M, Amorós-Galicia L, Krus S, Martin K, Herzog B
Journal of photochemistry and photobiology. B, Biology, 2020
Effect of emollients on UV filter absorbance and sunscreen efficiency.
Sohn M, Amorós-Galicia L, Krus S, Martin K, Herzog B
Journal of photochemistry and photobiology. B, Biology, 2020
Effect of emollients on UV filter absorbance and sunscreen efficiency.
Sohn M, Amorós-Galicia L, Krus S, Martin K, Herzog B
Journal of photochemistry and photobiology. B, Biology, 2020
Efficacy of a Rhealba® Oat Extract-based emollient on chr...
J Theunis, H Chaussade, O Bourgeois, V Mengeaud
Journal of the European Academy of Dermatology and Venereology : JEADV, 2017
Efficacy of a Rhealba® Oat Extract-based emollient on chr...
J Theunis, H Chaussade, O Bourgeois, V Mengeaud
Journal of the European Academy of Dermatology and Venereology : JEADV, 2017
Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment.
Vukašinović M, Savić S, Cekić N, Ilić T, Pantelić I et al.
Pharmaceutics, 2023
Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment.
Vukašinović M, Savić S, Cekić N, Ilić T, Pantelić I et al.
Pharmaceutics, 2023
Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment.
Vukašinović M, Savić S, Cekić N, Ilić T, Pantelić I et al.
Pharmaceutics, 2023
Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment.
Vukašinović M, Savić S, Cekić N, Ilić T, Pantelić I et al.
Pharmaceutics, 2023
Efficient Development of Green Emulsifier/Emollient-Based Emulsion Vehicles: From RSM Optimal Experimental Design to Abridged In Vivo Assessment.
Vukašinović M, Savić S, Cekić N, Ilić T, Pantelić I et al.
Pharmaceutics, 2023
Verified Feb 2026
Data: CosIng · EWG · CIR