Polyquaternium-45
AKA “PQ-45, Polyquaternium-45
Synthetic
Ingredient Facts
Polyquaternium-45
AKA: PQ-45
Synthetic · Film Forming · EWG: 4
Synthetic
Occlusive
Synthetic
Clean
Helps reduce frizz and flyaways while creating a lightweight protective layer that keeps hair smooth and styled throughout the day.
CAS #
221225-18-9
Form
Powder
See origin →
Functions
Antistatic
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Hair Fixing
Reduces Static
Creates Protective Barrier
Creates protective layer
Reduces flyaways
Holds hair in place
Traditional Use
A synthetic polymer developed in the 2000s for cosmetic use. Designed to provide superior conditioning and styling benefits with improved sensory profile and compatibility in complex formulations.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: CosIng · EWG · CIR