Potassium Glycyrrhetinate
AKA “Monopotassium glycyrrhetin, UNII-5850KHR68O, Glycyrrhetic acid potassium salt vinyals, ENOXOLONE POTASSIUM, ENOXOLONE MONOPOTASSIUM, Olean-12-en-29-oic acid, monopotassium salt, (3beta”
Synthetic
Ingredient Facts
Potassium glycyrrhetinate
AKA: Monopotassium glycyrrhetin, UNII-5850KHR68O, Glycyrrhetic acid potassium salt vinyals, ENOXOLONE POTASSIUM, ENOXOLONE MONOPOTASSIUM, Olean-12-en-29-oic acid, Monopotassium salt, (3beta
Synthetic · Antioxidant · EWG: 4
Synthetic
Antioxidant
Soothing
Skin Conditioner
Synthetic
Clean
A soothing plant-derived ingredient that calms and conditions skin, helping to reduce irritation and support a healthy complexion.
Formula
C30H45KO4
Mol. Weight
508.80
CAS #
85985-61-1
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Locks in moisture
Traditional Use
A processed derivative of licorice root (Glycyrrhiza glabra), which has been used in Traditional Chinese Medicine and Ayurveda for thousands of years for skin soothing and anti-inflammatory effects. The potassium salt form was developed to stabilize licorice's active compounds in modern cosmetics.
Skin Types
●all-skin-types
Best For
Irritation
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Final Report on the Safety Assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammon
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Potassium Glycyrrhetinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate,
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2007
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR