Quassin
AKA “(+)-Quassin, NSC-36342, (1S, 16-trione, Picrasa-2, 17-tetramethyl-10-oxatetracyclo(7.7.1.02
Synthetic
Ingredient Facts
Quassin
AKA: (+)-Quassin, NSC-36342, (1S, 16-trione, Picrasa-2, 17-tetramethyl-10-oxatetracyclo(7.7.1.02
Synthetic · Denaturant · EWG: 5
Synthetic
Skin Conditioner
Synthetic
Clean
A plant-derived ingredient that helps stabilize formulas and improve product texture, ensuring your beauty products perform their best.
Formula
C22H28O6
Mol. Weight
388.50
CAS #
76-78-8, 75991-65-0
Form
Liquid
See origin →
Functions
Denaturant
Bitter Masking
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Makes Alcohol Undrinkable
Fights Bacteria
Antioxidant Protection
Reduces Inflammation
Traditional Use
Quassin is a bitter compound extracted from quassia wood, which has been used in traditional medicine in the Caribbean and South America for its antimicrobial and anti-parasitic properties. It has been incorporated into modern skincare for potential skin-clarifying benefits.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
5
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR