Quassin
AKA “76-78-8, (+)-Quassin, QP1YAK6QGK, DTXSID30878613, NSC-36342, (1S, 2S, 6S, 7S, 9R, 13R, 17S)-4, 15-dimethoxy-2, 6, 14, 17-tetramethyl-10-oxatetracyclo[7.7.1.02, 7.013, 17]heptadeca-4, 14-diene-3, 11, 16-trione, Picrasa-2, 12-diene-1, 2, 12-dimethoxy-, 17-tetramethyl-10-oxatetracyclo(7.7.1.02, 17)heptadeca-4, RefChem:178048
Ingredient
Ingredient Facts
Quassin
AKA: 76-78-8, (+)-Quassin, QP1YAK6QGK, DTXSID30878613, NSC-36342, (1S, 2S, 6S, 7S, 9R, 13R, 17S)-4, 15-dimethoxy-2, 6, 14, 17-tetramethyl-10-oxatetracyclo[7.7.1.02, 7.013, 17]heptadeca-4, 14-diene-3, 11, 16-trione, Picrasa-2, 12-diene-1, 2, 12-dimethoxy-, 17-tetramethyl-10-oxatetracyclo(7.7.1.02, 17)heptadeca-4, RefChem:178048
Ingredient · Denaturant · EWG: 5
Synthetic
Not Clean
(3aS,6aR,7aS,8S,11aS,11bS,11cS)-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-Dodecahydro-2,10-dimethoxy-3,8,11a,11c-tetramethyldibenzo[de,g]chromene-1,5,11-trione
Formula
C22H28O6
Mol. Weight
388.50
CAS #
76-78-8, 75991-65-0
Form
Liquid
See origin →
Functions
Denaturant
Makes Alcohol Undrinkable
Fights Bacteria
Antioxidant Protection
Reduces Inflammation
Traditional Use
Quassin is a bitter compound extracted from quassia wood, which has been used in traditional medicine in the Caribbean and South America for its antimicrobial and anti-parasitic properties. It has been incorporated into modern skincare for potential skin-clarifying benefits.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR