Ribonolactone
AKA “(3R, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-one, D-Ribono-gamma-lactone, Ribonic acid, gamma-lactone, NSC-1031, RefChem:883599, D-Ribono-1
Synthetic
Ingredient Facts
Ribonolactone
AKA: (3R, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-one, D-Ribono-gamma-lactone, Ribonic acid, Gamma-lactone, NSC-1031, RefChem:883599, D-Ribono-1
Synthetic · Humectant · EWG: 4
Synthetic
Humectant
Skin Conditioner
Synthetic
Clean
A naturally derived humectant that draws moisture into skin and hair, helping to keep them hydrated and soft throughout the day.
Formula
C5H8O5
Mol. Weight
148.11
CAS #
5336-08-3
Form
Liquid
State
Solid
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
A synthetic nucleoside derivative developed in the late 20th century for cosmetic and pharmaceutical applications. Created to provide nucleic acid precursors that support cellular function and skin health.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR