Silybum marianum ethyl ester
AKA “Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Synthetic
Ingredient Facts
Silybum marianum ethyl ester
AKA: Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Synthetic · Antioxidant · EWG: 4
Plant-Derived Synthetic
Antioxidant
Soothing
Skin Conditioner
Synthetic
Clean
Milk thistle seed extract that helps condition and soften skin. This Mediterranean plant has been treasured for centuries for its nourishing properties.
CAS #
84604-20-6
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Locks in moisture
Traditional Use
Milk thistle (Silybum marianum) has been used in European and traditional medicine since ancient Greece for liver and skin health. The ethyl ester form is a modern extraction designed to preserve the plant's active silymarin compounds.
Skin Types
all-skin-types
Best For
Irritation
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: Kew POWO · CosIng · EWG · CIR