Sodium Isopropylparaben
AKA “Isopropylparaben Sodium Salt, Preservative
Synthetic
Ingredient Facts
Sodium isopropylparaben
AKA: Isopropylparaben Sodium Salt, Preservative
Synthetic · Antimicrobial · EWG: 4
Synthetic
Preservative
Synthetic
Not Clean
Sodium salt of Isopropylparaben Science: Functions: Preservative Safety Ratings: CIR: Safe as used EU Restriction: II/1374
CAS #
99-76-3; 26112-07-2
Form
Powder
See origin →
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Anti-Inflammatory
Fights Acne
Prevents microbial growth
Traditional Use
A synthetic preservative from the paraben family developed in the 20th century with no traditional use. Formulated to provide antimicrobial protection in modern cosmetic and pharmaceutical formulations.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
Dermal absorption: 0.1%. Source: CIR Safety Assessment (CIR Seq 746).
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Characterization of photoproducts and global ecotoxicity of chlorphenesin: A preservative used in skin care products.
Ben Ouaghrem M, de Vaugelade S, Bourcier S, Genty C, Pirnay S et al.
International journal of cosmetic science, 2022
Deciphering trends in replacing preservatives in cosmetics intended for infants and sensitive population.
Chen T, Chang H
Scientific reports, 2024
Sodium Isopropylparaben
European Commission
EU Cosmetic Ingredient Database (CosIng)
Safety review of phenoxyethanol when used as a preservative in cosmetics.
Dréno B, Zuberbier T, Gelmetti C, Gontijo G, Marinovich M
Journal of the European Academy of Dermatology and Venereology : JEADV, 2019
Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract.
Ganzera M, Aberham A, Stuppner H
Journal of agricultural and food chemistry, 2006
Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract.
Ganzera M, Aberham A, Stuppner H
Journal of agricultural and food chemistry, 2006
d) Non-oral products as a preservative
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Preservatives in Personal Hygiene and Cosmetic Products, Topical Medications, and Household Cleaners in Spain.
Pastor-Nieto MA, Alcántara-Nicolás F, Melgar-Molero V, Pérez-Mesonero R, Vergara-Sánchez A et al.
Actas dermo-sifiliograficas, 2017
Scientific Advice on the safety of Thiomersal (CAS No. 54-64-8, EC No. 200-210-4) and Phenylmercuric salts as preservatives in cosmetic products
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
Effect of cosmetic chemical preservatives on resident flo...
Qian Wang, Shumei Cui, Li Zhou, Keke He, Liya Song, Haiyan Liang + 1 more
Journal of cosmetic dermatology, 2019
Contact dermatitis caused by preservatives.
Elizabeth Yim, Katherine L Baquerizo Nole, Antonella Tosti
Dermatitis : contact, atopic, occupational, drug, 2014
Verified Feb 2026
Data: CosIng · EWG · CIR