Tetramethyl Acetyloctahydronaphthalenes
AKA “OTNE, Iso E Super
Synthetic
Ingredient Facts
Tetramethyl acetyloctahydronaphthalenes
AKA: OTNE, Iso E Super
Synthetic · Perfuming · EWG: 4
Synthetic
Fragrance
Skin Conditioner
Synthetic
Clean
A woody fragrance ingredient that adds a subtle scent while helping to condition and soften skin.
CAS #
54464-57-2, 54464-59-4, 68155-66-8, 68155-67-9
See origin →
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic polycyclic compound developed in the mid-20th century for use as a fragrance ingredient and solvent in cosmetics. It provides a woody, musky scent profile and was created to offer stability and longevity in fragrance formulations.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
EWG
4
CIR
Insufficient
Pregnancy
CIR Safety Findings
ewg-4
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: CosIng · EWG · CIR