Tocopherol
Vitamin
Ingredient Facts
Tocopherol
Vitamin · Antioxidant · EWG: 2
Varies With Manufacturer
Antioxidant
Skin Conditioner
Vitamin
Clean
Vitamin E from Spain that protects skin from environmental damage and keeps it soft and moisturized. A powerful antioxidant that helps maintain healthy, youthful-looking skin.
Formula
C28H48O2
Mol. Weight
416.70
CAS #
54-28-4, 16698-35-4, 10191-41-0, 119-13-1, 1406-18-4, 1406-66-2, 2074-53-5, 59-02-9, 7616-22-0
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Neutralizes free radicals
Prevents moisture loss
Traditional Use
Appears to be a malformed or incomplete chemical identifier; unable to provide meaningful historical information without a valid CAS number or INCI name.
Skin Types
all-skin-types, gentle
Best For
General
Melanin-Rich Skin
Highly Suitable
EWG
2
CIR
Insufficient
Pregnancy
CIR Safety Findings
Not a Sensitizer
ewg-2
medical-approval
pregnancy-nursing-safe
all-shades-safe
Concentration Guide
Dermal absorption: 1%. Source: CIR Safety Assessment (CIR Seq 667).
Regulatory Status
USAunder review
CANADApermitted
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Final Report on the Safety Assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilano
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Tocopherol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Tocopherol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Development of phospholipid nanoparticles encapsulating 3-O-cetyl ascorbic acid and tocopherol acetate (TA-Cassome) for improving their skin accumulat
Fushimi T, Uchino T, Miyazaki Y, Hatta I, Asano M et al.
International journal of pharmaceutics, 2018
Suppression of menthyl anthranilate (UV-A sunscreen)-sensitized singlet oxygen generation by Trolox and α-tocopherol.
Kitasaka S, Yagi M, Kikuchi A
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2020
Processing impact on tocopherols and triglycerides composition of soybean oil and its deodorizer distillate evaluated by high-performance liquid chrom
Laghari ZH, Sherazi STH, Ayyildiz HF, Topkafa M, Kara H et al.
Turkish journal of chemistry, 2020
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Toc
Zondlo Fiume M
International journal of toxicology, 2002
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR