Allantoin Galacturonic Acid
AKA “UNII-M25U72FT59, Allantoin, monogalactopyranuronate, Allantoin galacturonic acid [INCI], RefChem:110744, DTXCID90121697, 5-dioxoimidazolidin-4-yl)urea;(2S, 6-tetrahydroxyoxane-2-carboxylic acid”
Synthetic
Ingredient Facts
Allantoin galacturonic acid
AKA: UNII-M25U72FT59, Monogalactopyranuronate, Allantoin galacturonic acid [INCI], RefChem:110744, DTXCID90121697, 5-dioxoimidazolidin-4-yl)urea;(2S, 6-tetrahydroxyoxane-2-carboxylic acid
Synthetic · Soothing · EWG: 4
Varies With Manufacturer
Soothing
Skin Conditioner
Barrier Support
Wound Healer
Synthetic
Clean
A soothing compound that conditions and protects skin, helping calm irritation and maintain a healthy complexion.
Formula
C10H16N4O10
Mol. Weight
352.26
CAS #
5119-24-4
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Nourishing
Protecting
Traditional Use
A modern formulation combining allantoin (from traditional comfrey use for wound healing) with galacturonic acid (derived from plant cell walls). Created to enhance skin conditioning and anti-inflammatory benefits in contemporary skincare.
Skin Types
●all-skin-types
Best For
Irritation
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Concentration Guide
2%
0%3%
Reg. Limit
FDA OTC limit: 2% (Skin Protectant). Source: FDA OTC Monograph, 21 CFR 347.10.
Regulatory Agencies
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
Final report of the safety assessment of allantoin and its related complexes.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2010
Final Report of the Safety Assessment of Allantoin and its Related Complexes
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Allantoin
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin Ascorbate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin Biotin
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin Galacturonic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin Glycyrrhetinic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin Panthenol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin Polygalacturonic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Allantoin
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Allantoin Glycyrrhetinic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Allantoin Panthenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Allantoin-functionalized silk fibroin/sodium alginate tra...
Haojiang Xie, Qiao Bai, Fankai Kong, Yang Li, Xiaoying Zha, Lingqin Zhang + 4 more
International journal of biological macromolecules, 2022
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR