Phospholipids
AKA “Lipids, Membrane lipids
Synthetic
Ingredient Facts
Phospholipids
AKA: Membrane lipids
Synthetic · Emollient · EWG: 4
Synthetic
Humectant
Emollient
Occlusive
Skin Conditioner
Plant Oil
Synthetic
Clean
Phospholipids help strengthen your skin's natural barrier and lock in moisture, keeping skin soft and hydrated throughout the day.
CAS #
123465-35-0
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Locks in moisture
Traditional Use
Naturally occurring components of cell membranes used traditionally in fat-based skincare preparations. Modern cosmetics use them extensively as emulsifiers, conditioning agents, and delivery systems for active ingredients.
Skin Types
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
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Deposition of plant lipids after single application of a lip care product determined by confocal raman spectroscopy, corneometry and transepidermal wa
Bielfeldt S, Blaak J, Laing S, Schleißinger M, Theiss C et al.
International journal of cosmetic science, 2019
Two ceramide subfractions detectable in Cer(AS) position by HPTLC in skin surface lipids of non-lesional skin of atopic eczema.
Bleck O, Abeck D, Ring J, Hoppe U, Vietzke JP et al.
The Journal of investigative dermatology, 1999
Quantitative lipidomics profiling of skin surface lipids and skin barrier function evaluation in patients with acne vulgaris.
Cheng Y, Sun Q, Gao J, Liu Q, Tian H et al.
Archives of dermatological research, 2025
Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydro
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Glycine Soja (Soybean) Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycolipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydrolyzed Phospholipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Phospholipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Placental Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Triticum Aestivum (Wheat) Flour Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Triticum Vulgare (Wheat) Bran Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Triticum Vulgare (Wheat) Flour Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycolipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Phospholipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Triticum Vulgare (Wheat) Flour Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Mitigation of retinol-induced skin irritation by physiologic lipids: Evidence from patch testing.
Fang Y, Ying Y, Xiaolan W, Lin S, Chenlan X et al.
Journal of cosmetic dermatology, 2024
Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and t
González-Illán F, Ojeda-Torres G, Díaz-Vázquez LM, Rosario O
Journal of analytical toxicology, 2011
Cutaneous Permeation of a Percutaneously Applied Glucocorticoid Using Plant-Based Anionic Phospholipids in Hydrogenated Vegetable Oil: A Preliminary S
Greiner JV, Bhargava HN, Glonek T, Korb DR, Lindsay ME et al.
Medicina (Kaunas, Lithuania), 2022
Interaction between Sophorolipids and β-glucan in Aqueous...
Hiroaki Kaga, Masanori Orita, Koji Endo, Masaaki Akamatsu, Kenichi Sakai, Hideki Sakai
Journal of oleo science, 2024
Interaction between Sophorolipids and β-glucan in Aqueous...
Hiroaki Kaga, Masanori Orita, Koji Endo, Masaaki Akamatsu, Kenichi Sakai, Hideki Sakai
Journal of oleo science, 2024
Macrocystis pyrifera Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models.
Kok JML, Dowd GC, Cabral JD, Wise LM
International journal of molecular sciences, 2023
Macrocystis pyrifera Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models.
Kok JML, Dowd GC, Cabral JD, Wise LM
International journal of molecular sciences, 2023
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
Synthesis of specific deuterated derivatives of the long chained stratum corneum lipids [EOS] and [EOP] and characterization using neutron scattering.
Sonnenberger S, Eichner A, Schmitt T, Hauß T, Lange S et al.
Journal of labelled compounds & radiopharmaceuticals, 2017
Emerging Lipids from Arecaceae Palm Fruits in Brazil.
Teixeira GL, Ibañez E, Block JM
Molecules (Basel, Switzerland), 2022
Comprehensive Extraction and Biological Activities of Mycosporine-like Amino Acids and Glyceroglycolipids Extracts from Two Macroalgae Ecklonia kurome
Wei X, Hu X, Li T, Li Y, Yu Y et al.
Foods (Basel, Switzerland), 2025
Lipids and the Permeability and Antimicrobial Barriers of the Skin.
Wertz PW
Journal of lipids, 2018
Verified Feb 2026
Data: CosIng · EWG · CIR