1,10-Decanediol
AKA “Decamethylene glycol, Decamethylenediol, 10-Dihydroxydecane, 10-Decamethylenediol, alpha, omega-Decanediol, NSC-17165, SPEZIOL C 10/2”
Synthetic
Ingredient Facts
1,10-Decanediol
AKA: Decamethylene glycol, Decamethylenediol, 10-Dihydroxydecane, 10-Decamethylenediol, Alpha, Omega-Decanediol, NSC-17165, SPEZIOL C 10/2
Synthetic · Humectant · EWG: 1
Synthetic
Humectant
Solvent
Skin Conditioner
Synthetic
Clean
A lightweight solvent that helps blend and dissolve other ingredients in the formula, ensuring smooth application and even coverage on skin.
Formula
C10H22O2
Mol. Weight
174.28
CAS #
112-47-0
Form
Liquid
State
Solid; [Merck Index] White solid; [Sigma-Aldrich MSDS]
See origin →
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens Barrier
Antioxidant
Protects skin from free radical damage caused by UV, pollution, and stress
Moisturizing
Locks in moisture to keep skin soft and supple throughout the day
Dissolves other ingredients
Traditional Use
A synthetic humectant and preservative booster developed in the 20th century for cosmetic formulations. Created to provide enhanced hydration and preservation benefits beyond what traditional plant-based moisturizers could offer.
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Fragrance material review on alpha-amylcinnamyl alcohol.
Bhatia SP, Wellington GA, Cocchiara J, Lalko J, Letizia CS et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007
Fragrance material review on dihydro-alpha-terpineol.
Bhatia SP, McGinty D, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008
Final Report on the Safety Assessment of Sodium Alpha-Olefin Sulfonates
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of alpha-Amino Acids as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium alpha-Olefin Sulfonates
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
1,10-Decanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Alpha-Isomethyl Ionone
European Commission
EU Cosmetic Ingredient Database (CosIng)
Thioctic (Alpha Lipoic) Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
1,10-Decanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Alpha-Isomethyl Ionone
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Cholecalciferol, 1 Alpha,25 Dihydroxy
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
[Percutaneous absorption of drug from alpha-olefin oligomer gel bases].
Kaiho F, Hirose C, Shimizu A, Sunada K, Isoyama A et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1992
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
Effects of 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsor
Limat A, Hunziker T, Braathen LR
Archives of dermatological research, 1993
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ et al.
The Cochrane database of systematic reviews, 2020
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
Safety of alpha-arbutin and beta-arbutin in cosmetic products
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
Evaluation of the Synthesis and Skin Penetration Pathway of Folate-Conjugated Polymeric Micelles for the Dermal Delivery of Irinotecan and Alpha-Mango
Sirirak T, Subongkot T
Pharmaceutics, 2025
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
Improvement of Skin Condition Through RXR Alpha-Activating Materials.
Ye S, Lee S, Kang S, Jun SH, Kang NG
Biomolecules, 2025
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR