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Bisabolol
AKA “DTXCID3025964, 5-HEPTEN-2-OL, 3-Cyclohexene-1-methanol, alpha, (alphaR, (R*”
Synthetic
Ingredient Facts
Bisabolol
AKA: DTXCID3025964, 5-HEPTEN-2-OL, 3-Cyclohexene-1-methanol, Alpha, (alphaR, (R*
Synthetic · Soothing · EWG: 3
Varies With Manufacturer
Soothing
Fragrance
Skin Conditioner
Synthetic
Clean
A natural-derived soothing ingredient with a warm, nutty-coconut scent. Helps calm and condition skin while adding a subtle fragrance to the formula.
Solubility Practically insoluble or insoluble in water
Formula
C15H26O
Mol. Weight
222.37
CAS #
515-69-5, 23089-26-1
Form
Powder
See origin →
Functions
Fragrance
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Quells irritation
Traditional Use
The CAS number for Glycerin, an alcohol compound first isolated from fats in the early 19th century. Widely used in traditional and modern cosmetics as a humectant and skin softener.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
EWG
3
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
all-shades-safe
Phototoxicity Concern
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
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Fragrance material review on alpha-amylcinnamyl alcohol.
Bhatia SP, Wellington GA, Cocchiara J, Lalko J, Letizia CS et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007
→
Fragrance material review on dihydro-alpha-terpineol.
Bhatia SP, McGinty D, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008
→
Final Report on the Safety Assessment of Bisabolol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Sodium Alpha-Olefin Sulfonates
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of alpha-Amino Acids as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Sodium alpha-Olefin Sulfonates
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Alpha-Isomethyl Ionone
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Thioctic (Alpha Lipoic) Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Alpha-Isomethyl Ionone
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Bisabolol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Cholecalciferol, 1 Alpha,25 Dihydroxy
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Alpha-hydroxy acids, including polyhydroxy acids and bionic acids with alpha hydroxyl groups, and their salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
[Percutaneous absorption of drug from alpha-olefin oligomer gel bases].
Kaiho F, Hirose C, Shimizu A, Sunada K, Isoyama A et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1992
→
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
→
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
→
Effects of antioxidant polyphenols on TNF-alpha-related diseases.
Kawaguchi K, Matsumoto T, Kumazawa Y
Current topics in medicinal chemistry, 2011
→
Facile Fabrication of α-Bisabolol Nanoparticles with Improved Antioxidant and Antibacterial Effects.
Kim S, Yu S, Kim J, Khaliq NU, Choi WI et al.
Antioxidants (Basel, Switzerland), 2023
→
Effects of 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsor
Limat A, Hunziker T, Braathen LR
Archives of dermatological research, 1993
→
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu H, Yu H, Xia J, Liu L, Liu GJ et al.
The Cochrane database of systematic reviews, 2020
→
α-(-)-bisabolol reduces pro-inflammatory cytokine product...
Anil K Maurya, Monika Singh, Vijaya Dubey, Suchita Srivastava, Suaib Luqman, Dnyaneshwar U Bawankule
Current pharmaceutical biotechnology, 2014
→
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
→
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
→
Uptake and bioconversion of alpha-tocopheryl acetate to a...
E P Norkus, G F Bryce, H N Bhagavan
Photochemistry and photobiology, 1993
→
Safety of alpha-arbutin and beta-arbutin in cosmetic products
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
→
Evaluation of the Synthesis and Skin Penetration Pathway of Folate-Conjugated Polymeric Micelles for the Dermal Delivery of Irinotecan and Alpha-Mango
Sirirak T, Subongkot T
Pharmaceutics, 2025
→
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
→
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
→
The Efficacy of Topical Cosmetic Containing Alpha-Arbutin...
Pimpa Tantanasrigul, Apinya Sripha, Bunchai Chongmelaxme
Journal of cosmetic dermatology, 2025
→
Corneal antinociceptive effect of (-)-α-bisabolol.
Teixeira GF, Costa FN, Campos AR
Pharmaceutical biology, 2017
→
Improvement of Skin Condition Through RXR Alpha-Activating Materials.
Ye S, Lee S, Kang S, Jun SH, Kang NG
Biomolecules, 2025
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR