C32-36 Isoalkyl Acid
AKA “Isoalkyl Acid, Fatty Acid
Synthetic
Ingredient Facts
C32-36 isoalkyl acid
AKA: Fatty Acid
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Barrier Lipid
Synthetic
Clean
C32-36 Isoalkyl Acid is a mixture of branched, saturated fatty acids with 32 to 36 carbons in the alkyl chain, isolated from Lanolin Acid Science: Functions: Skin Conditioning Safety Ratings: CIR: Safe as used
CAS #
68201-22-9
Form
Liquid
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks in moisture
Traditional Use
A synthetic branched-chain fatty acid developed for cosmetic formulations as a conditioning and emollient agent, offering stability advantages over natural fatty acids.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Aalto-Korte K, Pesonen M, Kuuliala O, Suuronen K
Contact dermatitis, 2014
Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Aalto-Korte K, Pesonen M, Kuuliala O, Suuronen K
Contact dermatitis, 2014
Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Aalto-Korte K, Pesonen M, Kuuliala O, Suuronen K
Contact dermatitis, 2014
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
Dietary influences of evening primrose and fish oil on the skin of essential fatty acid-deficient guinea pigs.
Chapkin RS, Ziboh VA, McCullough JL
The Journal of nutrition, 1987
Final Report: Safety Assessment of Fatty Acids and Fatty Acid Salts as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Fatty Acid Amidopropyl Dimethylamines as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Plant-Derived Fatty Acid Oils
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tripeptide-1, Hexapeptide-12 Their Metal Salts and Fatty Acid Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
C10-40 Isoalkyl Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
C10-40 Isoalkyl Acid Octyldodecanol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
C10-40 Isoalkyl Acid Phytosterol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
C10-40 Isoalkyl Acid Triglyceride
European Commission
EU Cosmetic Ingredient Database (CosIng)
C14-28 Isoalkyl Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
C32-36 Isoalkyl Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ethylhexyl C10-40 Isoalkyl Acidate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dietary olive oil intake aggravates psoriatic skin inflammation in mice via Nrf2 activation and polyunsaturated fatty acid imbalance.
Donato-Trancoso A, Correa Atella G, Romana-Souza B
International immunopharmacology, 2022
C14-28 Isoalkyl Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
A comparison of the physicochemical properties and fatty acid composition of indaiá (Attalea dubia) and Babassu (Orbignya phalerata) oils.
Ferreira BS, Faza LP, Le Hyaric M
TheScientificWorldJournal, 2012
Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and t
González-Illán F, Ojeda-Torres G, Díaz-Vázquez LM, Rosario O
Journal of analytical toxicology, 2011
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
Eye and skin irritation tests on the rabbit of several fatty acid esters.
Guillot JP, Giauffret JY, Martini MC, Gonnet JF, Soulé G
International journal of cosmetic science, 1979
The effect of dietary camelina, flaxseed, and canola oil supplementation on skin fatty acid profile and immune and inflammatory responses in healthy a
Hartwig S, Burron S, Richards T, Rankovic A, Ma DWL et al.
Journal of animal science, 2025
Cosmetic and Therapeutic Applications of Fish Oil's Fatty Acids on the Skin.
Huang TH, Wang PW, Yang SC, Chou WL, Fang JY
Marine drugs, 2018
Effect of dietary supplementation with omega-3 fatty acid...
Jae Yoon Jung, Hyuck Hoon Kwon, Jong Soo Hong, Ji Young Yoon, Mi Sun Park, Mi Young Jang + 1 more
Acta dermato-venereologica, 2014
Effect of dietary supplementation with omega-3 fatty acid...
Jae Yoon Jung, Hyuck Hoon Kwon, Jong Soo Hong, Ji Young Yoon, Mi Sun Park, Mi Young Jang + 1 more
Acta dermato-venereologica, 2014
Borage oil restores acidic skin pH by up-regulating the activity or expression of filaggrin and enzymes involved in epidermal lactate, free fatty acid
Kim KP, Jeon S, Kim MJ, Cho Y
Nutrition research (New York, N.Y.), 2018
Borage oil restores acidic skin pH by up-regulating the activity or expression of filaggrin and enzymes involved in epidermal lactate, free fatty acid
Kim KP, Jeon S, Kim MJ, Cho Y
Nutrition research (New York, N.Y.), 2018
Genetic inactivation of the Carnitine/Acetyl-Carnitine mitochondrial carrier of Yarrowia lipolytica leads to enhanced odd-chain fatty acid production.
Messina E, de Souza CP, Cappella C, Barile SN, Scarcia P et al.
Microbial cell factories, 2023
Fatty acid sulphoalkyl amides and esters as cosmetic surfactants.
Petter PJ
International journal of cosmetic science, 1984
Fatty acid sulphoalkyl amides and esters as cosmetic surfactants.
Petter PJ
International journal of cosmetic science, 1984
Polyglycerol fatty acid ester surfactant-based microemulsions for targeted delivery of ceramide AP into the stratum corneum: formulation, characterisa
Sahle FF, Metz H, Wohlrab J, Neubert RH
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012
The essential fatty acids.
Sardesai VM
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 1992
Fatty acid composition and productive traits of broiler fed diets containing conjugated linoleic acid.
Sirri F, Tallarico N, Meluzzi A, Franchini A
Poultry science, 2003
In vitro human skin barrier modulation by fatty acids: skin permeation and thermal analysis studies.
Tanojo H, Bouwstra JA, Junginger HE, Boddé HE
Pharmaceutical research, 1997
Screening of fatty acids, saccharides, and phytochemicals in Jatropha curcas seed kernel as their trimethylsilyl derivatives using gas chromatography/
Thi HT, Le BA, Le HNT, Okitsu K, Imamura K et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018
Verified Feb 2026
Data: CosIng · EWG · CIR