Niacinamide (Vitamin B3)
AKA “Niacinamide, Vitamin B3
Vitamin B3
Ingredient Facts
Niacinamide (Vitamin B3)
Vitamin B3 · Antioxidant · EWG: 4
Varies With Manufacturer
Antioxidant
Soothing
Skin Conditioner
B Vitamin
Vitamin B3
Clean
Niacinamide, a form of Vitamin B3, helps refine skin texture and minimize the appearance of pores for a smoother complexion.
CAS #
98-92-0
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Strengthens skin barrier
Brightens uneven skin tone
Reduces redness
Minimizes pores
Evens pigmentation
Traditional Use
Vitamin B3 was first identified in 1937. Niacinamide's skincare benefits were extensively researched beginning in the 1990s, when studies demonstrated its effectiveness for improving skin barrier function, reducing inflammation, and minimizing pore appearance.
Skin Types
all-skin-types
Best For
Pores
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Use Caution With
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
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Niacinamide Improves Aging Skin Appearance
Bissett DL, Oblong JE, Berge CA
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Final Report on the Safety Assessment of Niacinamide and Niacin
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Niacinamide
European Commission
EU Cosmetic Ingredient Database (CosIng)
Niacinamide (Vitamin B3)
European Commission
EU Cosmetic Ingredient Database (CosIng)
Niacinamide
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Niacinamide - mechanisms of action and its topical use in...
Johannes Wohlrab, Daniela Kreft
Skin pharmacology and physiology, 2014
Niacinamide - mechanisms of action and its topical use in...
Johannes Wohlrab, Daniela Kreft
Skin pharmacology and physiology, 2014
Niacinamide - mechanisms of action and its topical use in...
Johannes Wohlrab, Daniela Kreft
Skin pharmacology and physiology, 2014
Niacinamide Mechanisms of Action
Wohlrab J, Kreft D
Skin Pharmacology and Physiology, 2014
Niacinamide - mechanisms of action and its topical use in dermatology.
Wohlrab J, Kreft D
Skin pharmacology and physiology, 2014
Niacinamide - mechanisms of action and its topical use in dermatology.
Wohlrab J, Kreft D
Skin pharmacology and physiology, 2014
Niacinamide - mechanisms of action and its topical use in dermatology.
Wohlrab J, Kreft D
Skin pharmacology and physiology, 2014
An Investigation of the Influence of PEG 400 and PEG-6-Caprylic/Capric Glycerides on Dermal Delivery of Niacinamide.
Zhang Y, Lane ME, Moore DJ
Polymers, 2020
Dermal Delivery of Niacinamide-In Vivo Studies.
Zhang Y, Kung CP, Iliopoulos F, Sil BC, Hadgraft J et al.
Pharmaceutics, 2021
Dermal Delivery of Niacinamide-In Vivo Studies.
Zhang Y, Kung CP, Iliopoulos F, Sil BC, Hadgraft J et al.
Pharmaceutics, 2021
Verified Feb 2026
Data: CosIng · EWG · CIR