undefined 1
undefined 2
Hyaluronic Acid
Acid
Ingredient Facts
Hyaluronic acid
Acid · Humectant · EWG: 1
Varies With Manufacturer
Humectant
Skin Conditioner
Hyaluronic Acid
Acid
Clean
Hyaluronic Acid is a powerful humectant that draws moisture deep into skin, helping it stay hydrated, plump, and smooth throughout the day.
CAS #
9004-61-9
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
Discovered in 1934 in bovine eye tissues; originally identified as a component of the extracellular matrix. Recognized in skincare from the 1990s onward for its exceptional water-binding capacity, inspired by the body's natural hyaluronic acid found in skin, joints, and connective tissue.
Skin Types
â—Źall-skin-types, gentle
Best For
Dehydration
Melanin-Rich Skin
Highly Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Potential Sensitizer
Regulatory Status
USAâś” permitted
EUâš  restricted
JAPANâš  restricted
CANADAâš  restricted
Slip Tint™ Tinted Moisturizer
Saie
 →
Sunvisor™
Saie
 →
Mini Sunvisor™
Saie
 →
Glowy Super Skin Tint Foundation
Saie
 →
Glow Sculpt™
Saie
 →
Glossybounce™
Saie
 →
Slip Tint™ Radiant All-Over Concealer
Saie
 →
Bestsellers Bundle
Saie
 →
Complexion Boost
Saie
 →
Saieglow™ Duo
Saie
 →
Concealer Brush Duo
Saie
 →
Skin Glow Duo
Saie
 →
Slip Brush Duo
Saie
 →
Glossybounce™ Duo
Saie
 →
Lip Combo
Saie
 →
Super Skin Duo
Saie
 →
The Allure Bundle 2024
Saie
 →
The Slip Tint™ Family
Saie
 →
SuperSuede™ Baked Powder Blush
Saie
 →
The SuperSuede™ Stack
Saie
 →
The Blush Stack
Saie
 →
Slip Tint™ Undetectable Baked Setting Powder
Saie
 →
Glossybounce™ Duo
Saie
 →
SuperSuede™ Radiant Baked Bronzer
Saie
 →
Vital Rush™ Skin Renewal Serum
COOLA
 →
Rewakening™ Rosewater Mist
COOLA
 →
Refreshing Water Cream
COOLA
 →
Refreshing Water Hydration Stick
COOLA
 →
Refreshing Water Plumping Gel Serum
COOLA
 →
Clean-ical Formulations AM + PM Serum Duo
Odacité
 →
Derm-Restore Super Serum • Edelweiss Extrême® • Peptides + Carnosine
Odacité
 →
Edelweiss Extrême® • Repair + Restore Set
Odacité
 →
Sun Defense Performance Duo • SPF 50 + Super Serum
Odacité
 →
Anti-aging Dream Duo • SPF 50 + Retinol
Odacité
 →
Bioactive Renew Supreme Cream • Edelweiss Extrême® • Peptides + Carnosine
Odacité
 →
Edelweiss Extrême® Skin Barrier Set
Odacité
 →
Age-Defying Fundamentals
Odacité
 →
Day & Night Eye Care Duo
Odacité
 →
Sun Damage Defense Duo • SPF 50 + Vitamin C
Odacité
 →
Anti Aging Eye & Sun Defense Duo
Odacité
 →
SPF 50 Color Balm Duo
Odacité
 →
SPF 50 Tinted Sunscreen & Color Balm Duo
Odacité
 →
Winter Renewal Ritual
Odacité
 →
Love + Rose Hydrating Serum
One Love Organics
 →
Needle-less
Goldfaden MD
 →
Light Treatment
Goldfaden MD
 →
Doctor's Scrub Advanced
Goldfaden MD
 →
Plant Profusion Energetic Eye Cream
Goldfaden MD
 →
Plant Profusion Neck Cream
Goldfaden MD
 →
Plant Profusion Night Cream
Goldfaden MD
 →
Hyaluronic Acid: Redefining Its Role.
Abatangelo G, Vindigni V, Avruscio G, Pandis L, Brun P
Cells, 2020
→
Final report of the safety assessment of hyaluronic acid,...
Lillian C Becker, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, James G Marks, Ronald C Shank + 3 more
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid,...
Lillian C Becker, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, James G Marks, Ronald C Shank + 3 more
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid,...
Lillian C Becker, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, James G Marks, Ronald C Shank + 3 more
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate.
Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence.
Bravo B, Correia P, Gonçalves Junior JE, Sant'Anna B, Kerob D
Dermatologic therapy, 2022
→
Benefits of topical hyaluronic acid for skin quality and ...
Bruna Bravo, Priscila Correia, José Euzébio Gonçalves Junior, Beatriz Sant'Anna, Delphine Kerob
Dermatologic therapy, 2022
→
Final Report on the Safety Assessment of Hyaluronic Acid, Sodium Hyaluronate, and Potassium Hyaluronate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Hyaluronic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hydrolyzed Hyaluronic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
A review of the metabolism of 1,4-butanediol diglycidyl ether-crosslinked hyaluronic acid dermal fillers.
De Boulle K, Glogau R, Kono T, Nathan M, Tezel A et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013
→
A review of the metabolism of 1,4-butanediol diglycidyl ether-crosslinked hyaluronic acid dermal fillers.
De Boulle K, Glogau R, Kono T, Nathan M, Tezel A et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013
→
A review of the metabolism of 1,4-butanediol diglycidyl ether-crosslinked hyaluronic acid dermal fillers.
De Boulle K, Glogau R, Kono T, Nathan M, Tezel A et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013
→
A review of the metabolism of 1,4-butanediol diglycidyl ether-crosslinked hyaluronic acid dermal fillers.
De Boulle K, Glogau R, Kono T, Nathan M, Tezel A et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013
→
Hyaluronic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hydrolyzed Hyaluronic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hyaluronic acid-lipid binding.
Ewurum A, Alur AA, Glenn M, Schnepf A, Borchman D
BMC chemistry, 2021
→
Hyaluronic acid-lipid binding.
Ewurum A, Alur AA, Glenn M, Schnepf A, Borchman D
BMC chemistry, 2021
→
Hyaluronic acid-lipid binding.
Ewurum A, Alur AA, Glenn M, Schnepf A, Borchman D
BMC chemistry, 2021
→
Hyaluronic acid-lipid binding.
Ewurum A, Alur AA, Glenn M, Schnepf A, Borchman D
BMC chemistry, 2021
→
Hyaluronic acid-lipid binding.
Ewurum A, Alur AA, Glenn M, Schnepf A, Borchman D
BMC chemistry, 2021
→
Hyaluronic Acid in the Third Millennium.
Fallacara A, Baldini E, Manfredini S, Vertuani S
Polymers, 2018
→
Effect of a New Hyaluronic Acid Hydrogel Dermal Filler Cr...
Yanping Guo, Wuhan Wei, Haoyu Wang, Qiang Li, Changzheng Wei, Jingyu Zhang + 1 more
Aesthetic surgery journal, 2023
→
Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a Porphyridium Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract.
Havas F, Krispin S, Cohen M, Attia-Vigneau J
Marine drugs, 2026
→
The key role of hyaluronic acid molecular weight in HIF-1...
Jing Liu, Meishan Piao, Yunxing Li, Cheng Yang, Bingtian Zhao
International journal of biological macromolecules, 2025
→
The key role of hyaluronic acid molecular weight in HIF-1...
Jing Liu, Meishan Piao, Yunxing Li, Cheng Yang, Bingtian Zhao
International journal of biological macromolecules, 2025
→
Fabrication of High-Resolution Fine Microneedles Derived from Hydrolyzed Hyaluronic Acid Gels in Vacuum Environment Imprinting Using Water Permeable M
Miura S, Yamagishi R, Miyazaki R, Yasuda K, Kawano Y et al.
Gels (Basel, Switzerland), 2022
→
Hyaluronic acid and HA-modified cationic liposomes for promoting skin penetration and retention.
Ni C, Zhang Z, Wang Y, Zhang Z, Guo X et al.
Journal of controlled release : official journal of the Controlled Release Society, 2023
→
Hyaluronic Acid and Skin Aging
Papakonstantinou E, Roth M, Karakiulakis G
Dermato-Endocrinology, 2012
→
Interconnected hyaluronic acid derivative-based nanoparticles for anticancer drug delivery.
Park JH, Cho HJ, Termsarasab U, Lee JY, Ko SH et al.
Colloids and surfaces. B, Biointerfaces, 2014
→
Hyaluronic Acid Anti-Wrinkle Efficacy
Pavicic T, Gauglitz GG, Lersch P, Schwach-Abdellaoui K, Malle B, Korting HC, Farwick M
Journal of Drugs in Dermatology, 2011
→
The efficacy of hyaluronic acid fragments with amino acid...
Antonio Scarano, E Qorri, A Sbarbati, S A Gehrke, Alessio Frisone, D Amuso + 1 more
Journal of ultrasound, 2024
→
Chitosan, alginate, hyaluronic acid and other novel multi...
Ningning Yuan, Kan Shao, Shan Huang, Cheng Chen
International journal of biological macromolecules, 2023
→
Hydrophobically-modified hyaluronic acid as stabilizer for oil-in-water emulsions to improve epidermis biodistribution of actives.
Zamora P, Movellan J, Grande HJ, Loinaz I, Dupin D
International journal of biological macromolecules, 2025
→
Verified Feb 2026
Data: CosIng · EWG · CIR
Hyaluronic Acid — Duck Heart Ghost